Search results for "Self recognition"
showing 3 items of 3 documents
A new hydrogen bonding motif involved in self-recognition in the solid state by functionalised macrocycles
2011
Self-recognition within the crystal lattices of three functionalised macrocycles results in the formation of arrays of remarkably similar hermaphroditic pairs of macrocycles. In the case of two of the macrocycles containing acylhydrazine substituents, a hitherto unknown recognition pattern is found in the interaction of the hydrazine moiety with crown-ether oxygen atoms.
Structural and functional diversity of the lectin repertoire in teleost fish: Relevance to innate and adaptive immunity
2011
Protein–carbohydrate interactions mediated by lectins have been recognized as key components of innate immunity in vertebrates and invertebrates, not only for recognition of potential pathogens, but also for participating in downstream effector functions, such as their agglutination, immobilization, and complement-mediated opsonization and killing. More recently, lectins have been identified as critical regulators of mammalian adaptive immune responses. Fish are endowed with virtually all components of the mammalian adaptive immunity, and are equipped with a complex lectin repertoire. In this review, we discuss evidence suggesting that: (a) lectin repertoires in teleost fish are highly dive…
Molecular Evolution of Defense Pathways in Sponges: Self–Self-recognition and Fight against the Nonself
2016
This article provides an overview of the immune system in poriferans at a tissue, cellular, and molecular level. Despite their simple organization, sponges have developed molecular mechanisms to recognize and resist foreign organisms. They are able to distinguish among food organisms, pathogens, and sponge-associated organisms. Although they lack specialized immune cells, sponges display molecular precursors, which are similar to molecular mediators involved in innate and adaptive immune systems, present in more evolutionarily advanced taxa, as outlined in succeeding articles in the Phylogeny section.